impact of acute exercise, hypertension and diabetes mellitus on antioxidant status in man

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University of Birmingham , Birmingham
Statementby Simon Robert Jenkinson Maxwell.
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The aim of our study was to evaluate oxidative stress in patients with diabetes mellitus type 2 and to determine influence of acute exercise training on the investigated parameters. The effects of exercise on myocardial antioxidant enzyme activities have been widely investigated.

It is generally believed that even short-term endurance exercise training results in rapid increases in myocardial Mn-SOD activity, which greatly impacts ischemic/reperfusion injury [81–83].Exercise also increases glutathione peroxidase activity in the liver, kidney, and heart [] as well as in Cited by: Atalay et al.

() demonstrated that moderate exercise (VO 2 60% for 40 min) did not alter antioxidant enzyme activity in erythrocytes of young men with diabetes.

However, acute and chronic. Physical activity has been associated with reduced oxidative stress (OS) in observational studies and clinical trials. The purpose of this systematic review and meta-analysis of controlled trials was to determine the effect of physical exercise on OS parameters.

We conducted a systematic review of the literature up to March that included the following databases: PubMed, SCOPUS, and Web of Cited by: The purposes of this chapter are to (1) overview the current consensus on the effects of acute (immediate, short-term, or postexercise hypotension) and chronic (long-term or training) exercise on blood pressure among individuals with prehypertension or established hypertension; (2) discuss new and emerging research on the effects of acute and.

Introduction. Physical exercise has been considered as one of the cornerstones in the treatment of diabetes mellitus along with nutrition and medication since from the past years ago [].Diabetes mellitus, a chronic metabolic disease, is characterized by an increase in the blood-glucose level resulting from a relative insulin deficiency or insulin resistance or both.

INTRODUCTION. It is estimated that % of Palestinians living in West-Bank have hypertension and % have diabetes mellitus.1 Although, no epidemiological data are available about Palestinians who have diabetes mellitus and hypertension together, the prevalence of hypertension, in general, is few times greater in patients with diabetes mellitus than in matched non-diabetic individuals.2 The.

Exercise promotes longevity and ameliorates type 2 diabetes mellitus and insulin resistance. However, exercise also increases mitochondrial formation of presumably harmful reactive oxygen species (ROS). Antioxidants are widely used as supplements but whether they affect the health-promoting effects of exercise is unknown.

Exercise in Resistant Hypertension Aerobic Exercise Reduces Blood Pressure in Resistant Hypertension of acute ischemia in exercise ECG, and change of antihypertensive Diabetes mellitus 4 () 6 () Hyperlipidemia 15 () 18 () Diabetes mellitus (DM) constitutes one of the most widespread health problems in the world, as it is estimated that its prevalence of million observed in will increase to million in the year [].The interactions of environmental and behavioral factors, such as physical inactivity, obesity, and stress, with genetic factors seem to be the main reason for the epidemic character.

Studies assessing the effects of acute exercise on several pathophysiological mechanisms in patients with essential hypertension Figures - uploaded by Eleni Gavriilaki Author content. DIABETES MELLITUS MANAGEMENT. There is no known cure for DM except in very specific situations.

Management of DM concentrates mostly on keeping blood sugar to normal levels as possible, which is usually accomplished with exercise, diet, and use of appropriate medications.[1,5,27,28]The complications of diabetes are less common and less severe in patients who have well-managed.

Significance: Over-nutrition and sedentary lifestyle has led to a worldwide increase in obesity, insulin resistance, and type 2 diabetes (T2D) associated with an increased risk of development of cardiovascular disorders.

Diabetic cardiomyopathy, independent of hypertension or coronary disease, is induced by a range of systemic changes and may through multiple processes result in functional. Preeclampsia. The incidence of preeclampsia has risen in the past 20 years 4 and will likely keep climbing as a result of the growing obesity pandemic 5 and the increased incidence of hypertension and diabetes mellitus.

6,7 Moreover, studies suggest that women who experience preeclampsia are more likely to develop cardiovascular diseases later in life. 8 Although the development of the disease.

In the case of diabetes and high blood pressure, these effects include: Types of Hypertension in Diabetes Mellitus 1. Essential hypertension 2. Hypertension consequent to nephropathy 3. reduction of acute myocardial infarction, car-diovascular events, and mortality.

N.V. Bhagavan, Chung-Eun Ha, in Essentials of Medical Biochemistry (Second Edition), Chronic Complications of Diabetes Mellitus. Chronic complications of diabetes mellitus stem from elevated plasma glucose levels and involve tissues that do not require insulin (e.g., lens, retina, peripheral nerve) for the uptake and metabolism of glucose.

In these tissues, the intracellular level of. In summary, we report that exercise training- and diet-induced weight loss cause significant reduction in biomarkers of oxidative stress, which may beneficially impact parameters of IR. Weight reduction by lifestyle modification is a means of reducing coprecipators of CHD and type 2 diabetes.

Type 1 diabetes is a challenging condition to manage for various physiological and behavioural reasons. Regular exercise is important, but management of different forms of physical activity is particularly difficult for both the individual with type 1 diabetes and the health-care provider.

People with type 1 diabetes tend to be at least as inactive as the general population, with a large. Thus, research regarding the relationship of hypertension, diabetes, and/or CVD with QoL based on population-based data is needed. For these reasons, this study examined the individual and joint effects of hypertension, diabetes, and CVD, which are the most common diseases among Korean elderly individuals, on QoL in this population.

Diabetes mellitus (DM) is a group of diseases characterised by metabolic disturbances with increasing prevalence worldwide. 1 Individuals with DM present several detrimental micro- and macrovascular complications such as retinopathy, nephropathy, neuropathy, atherosclerosis and coronary heart disease.

2,3 Accordingly, efforts for early diagnosis and appropriate management are.

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Exercise, as part of lifestyle modification, is known to be the first line of therapy for patients with type 2 diabetes (1), and, dating back as far as AD, Greek physicians prescribed exercise as a way to improve health (2).

Regular exercise provides many physiological and psychological benefits, including improvements in glycemic control (in most individuals), insulin sensitivity, blood.

Wojtaszewski, J F and Richter, E A. Effects of acute exercise and training on insul in action and sensitivity: focus on molecular mechanisms in mus cle.

Essays in Biochemistry 42 31 – But the most important ways to slow diabetes complications are to keep your blood sugar levels under control, eat right, exercise, lose weight, avoid smoking, and get high blood pressure and high.

This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions.

Hypertension is one of the major risk factors for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development of.

Hypertension is the most common, costly, and preventable cardiovascular disease risk factor. Numerous professional organizations and committees recommend exercise as initial lifestyle therapy to prevent, treat, and control hypertension.

Yet, these recommendations differ in the components of the Frequency, Intensity, Time, and Type (FITT) principle of exercise prescription (Ex.

ing type-2 diabetes mellitus and improving disease status but are also effective in the prevention and treatment of all other insulin-resistance-related diseases (lifestyle-related diseases), including hypertension and hyper-lipidemia, by improving in vivo sensitivity to insulin.

The incidence of diabetes mellitus de-creases by 6% with every.

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Iscoe KE, Riddell MC. Continuous moderate-intensity exercise with or without intermittent high-intensity work: Effects on acute and late glycaemia in ath-letes with Type 1 diabetes mellitus.

Diabet Med ;– Gordon BA, Benson AC, Bird SR, et al. Resistance training improves metabolic health in type 2 diabetes: A systematic review. Objective Both aerobic (AER) and resistance (RES) training, if maintained over a period of several months, reduce HbA1c levels in type 2 diabetes subjects.

However, it is still unknown whether the short-term effects of these types of exercise on blood glucose are similar. Our objective was to assess whether there may be a difference in acute blood glucose changes after a single bout of AER.

This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others.

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High blood pressure is estimated to account for approximately 13% of CVD deaths, while tobacco accounts for 9%, diabetes 6%, lack of exercise 6% and obesity 5%.

During exercise, whole-body oxygen consumption may increase by as much as fold, and even greater increases may occur in the working muscles. To meet its energy needs under these circumstances, skeletal muscle uses, at a greatly increased rate, its own stores of glycogen and triglycerides, as well as free fatty acids (FFAs) derived from the breakdown of adipose tissue triglycerides and.

Diabetes mellitus (DM), commonly known as diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. Symptoms often include frequent urination, increased thirst, and increased appetite. If left untreated, diabetes can cause many complications.

Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or.Angiotensin II receptor antagonists can reduce the pro-inflammatory and thrombogenic effects of hypercholesterolemia.(13) These and other drugs like ACE inhibitors that inhibit the renin-angiotensin system have also been shown to significantly reduce the incidence of Type 2 diabetes in patients with hypertension and congestive failure.(49 Sowers JR, Epstein M.

Diabetes mellitus and associated hypertension, vascular disease, and nephropathy: an update. Hypertension. ; – Crossref Medline Google Scholar; 50 Fotherby MD, Williams JC, Forster LA, Craner P, Ferns GA.

Effect of vitamin C on ambulatory blood pressure and plasma lipids in older persons.